Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 4 reviews · Musculoskeletal

No studies found 1 · 10%GRADE not reported 1 · 10%Very low 3 · 30%Low 4 · 40%Moderate 0 · 0%High 1 · 10%

Prefabricated foot orthoses vs shoes

Withdrawals due to adverse events · children with juvenile idiopathic arthritis and flat feet

Prefabricated foot orthoses showed no clear difference in withdrawal due to adverse events compared with shoes; GRADE not reported.

1 finding from 1 review

Intermittent/cyclic etidronate 400 mg/day vs placebo

Withdrawals due to adverse events · postmenopausal women with a higher risk for fracturesa

It is very uncertain whether intermittent/cyclic etidronate 400 mg/day changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review