What do systematic reviews say?

Enteral nutrition vs corticosteroids

It is very uncertain whether enteral nutrition changes withdrawal due to adverse events compared with corticosteroids (very low certainty).

• Enteral nutritional therapy for induction of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  RR 2.95 [1.02, 8.48]
  3 studies · 169 participants
  Very low

Enteral nutrition vs 6‐MP

The review found no eligible studies for this question.

• Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Enteral nutrition vs mesalamine

The review found no eligible studies for this question.

• Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Elemental vs non‐elemental enteral feeds

It is very uncertain whether elemental changes withdrawal due to adverse events compared with non‐elemental enteral feeds (very low certainty).

• Enteral nutritional therapy for induction of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  RR 1.37 [0.83, 2.25]
  7 studies · 272 participants
  Very low

Elemental formula supplements vs no supplementation

• Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 51 participants
  GRADE not reported

Elemental formula supplements vs polymeric formula supplements

Elemental formula supplements showed no clear difference in withdrawals due to adverse events compared with polymeric formula supplements (low certainty).

• Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  RR 9.75 [0.59, 159.93]
  1 study · 33 participants
  Low