Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews · Hepato-Biliary

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Sclerotherapy vs no intervention

Upper gastrointestinal bleeding · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis

It is very uncertain whether sclerotherapy changes upper gastrointestinal bleeding compared with no intervention (very low certainty).

1 finding from 1 review

Sclerotherapy versus sham or no intervention for primary prophylaxis of oesophageal variceal bleeding in children with… 2020 · Cochrane Headline outcomes only
RR 0.46 [0.26, 0.83]
1 study · 108 participants
Very low

Band ligation vs no intervention

Upper gastrointestinal bleeding · adults with oesophageal varices

Band ligation probably leads to lower upper gastrointestinal bleeding compared with no intervention (moderate certainty).

1 finding from 1 review

Band ligation versus no intervention for primary prevention of upper gastrointestinal bleeding in adults with… 2019 · Cochrane Headline outcomes only
RR 0.44 [0.28, 0.72]
6 studies · 637 participants
Moderate

Carvedilol vs beta‐blocker

Upper gastrointestinal bleeding · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes upper gastrointestinal bleeding compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Carvedilol versus traditional, non‐selective beta‐blockers for adults with cirrhosis and gastroesophageal varices 2018 · Cochrane Headline outcomes only
RR 0.77 [0.43, 1.37]
10 studies · 810 participants
Very low