Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Musculoskeletal

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No studies found 1 · 50%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

Abatacept (2 and 10mg/kg) + DMARDs/biologic vs placebo + DMARDs/biologic

Total serious adverse events · patients with rheumatoid arthritis

Abatacept (2 and 10mg/kg) + DMARDs/biologic showed no clear difference in total serious adverse events compared with placebo + DMARDs/biologic (moderate certainty).

1 finding from 1 review

Abatacept for rheumatoid arthritis 2009 · Cochrane Headline outcomes only
RR 1.05 [0.87, 1.28]
6 studies · 3151 participants
Moderate

Diacerein vs placebo

Total number of serious adverse events not measured · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Diacerein for osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found