Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 7 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 4 · 33.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 33.3%Moderate 3 · 25%High 1 · 8.3%

Low molecular weight heparin vs vitamin K antagonist (VKA)

Thrombocytopenia (up to 3 months)n · people with cancer with thrombosis prophylaxis and central venous catheters

Low‐molecular‐weight heparin (LMWH) probably leads to higher thrombocytopenia (up to 3 months)n compared with vitamin K antagonist (VKA) (moderate certainty).

1 finding from 1 review

Low molecular weight heparin vs vitamin K antagonist secondary prophylaxis

Thrombocytopenia (main analysis‐ active cancer) · patients with cancer with venous thromboembolism

Low molecular weight heparin secondary prophylaxis showed no clear difference in thrombocytopenia (main analysis‐ active cancer) compared with vitamin K antagonist secondary prophylaxis (low certainty).

1 finding from 1 review