Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics
Swelling (mean) · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)
Postoperative systemic antibiotics… showed no clear difference in swelling at 48 hours compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.
3 findings from 1 review
- Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes48 hoursSMD 0.04 [-0.47, 0.55]2 studies · 61 participantsGRADE not reported
- Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes24 hoursSMD 0.27 [-0.23, 0.78]2 studies · 62 participantsVery low
- Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults 2024 · Cochrane All outcomes72 hoursSMD 0.02 [-0.49, 0.52]2 studies · 61 participantsVery low