What do systematic reviews say?

Topical antiseptic vs no treatment

• Topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 180 participants
  Very low

Topical antibiotics vs acetic acid

It is very uncertain whether topical antibiotics changes suspected ototoxicity compared with acetic acid (very low certainty).

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

Topical quinolone vs povidone‐iodine

It is very uncertain whether topical antibiotics (quinolones) changes suspected ototoxicity compared with povidone‐iodine (very low certainty).

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Very low

Topical quinolone vs boric acid

The review found no eligible studies for this question.

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 204 participants
  Very low