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Evidence found and GRADE certainty

6 questions · 9 findings · 2 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 3 · 33.3%Very low 1 · 11.1%Low 5 · 55.6%Moderate 0 · 0%High 0 · 0%

Transillumination and OCT vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

Transillumination and OCT had a summary specificity of 0.82 (95% CrI 0.68, 0.91) for detecting enamel caries; low certainty.

1 finding from 1 review

Fluorescence-based devices vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

In the fully within-person analysis, fluorescence had a summary specificity of 0.88 (95% CrI 0.78, 0.94); ungraded.

2 findings from 1 review

Visual caries detection (ICDAS visual/visual-tactile inspection) vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

Visual or visual-tactile classification had a summary specificity of 0.81 (95% CrI 0.73, 0.87) for detecting enamel caries; low certainty.

2 findings from 1 review

Imaging (analog or digital radiographs) vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

Radiographic imaging had a summary specificity of 0.89 (95% CrI 0.83, 0.93) for detecting enamel caries; low certainty.

2 findings from 1 review

Electrical conductance or impedance vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)

Electrical conductance or impedance had a summary specificity of 0.72 (95% CrI 0.44, 0.89) for detecting enamel caries; low certainty.

1 finding from 1 review

Electrical conductance devices (electronic caries monitor (ECM) and/or CarieScan Pro), used as an adjunct to clinical oral examination vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity for detection of enamel caries · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or extracted teeth of…
1 finding from 1 review
  • Electrical conductance for the detection of dental caries 2021 · Cochrane All outcomes
    Up to 3 months between index test and reference standard (in vivo studies)
    SoF findings (HSROC; no summary operating point reported): 'ECM: specificity from 0.73 to 0.96 ... CarieScan Pro: specificity from 0 to 1.00'. Across all 7 studies (8 datasets), covering 719 tooth surfaces or sites (no…
    7 studies
    Very low