Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews

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No studies found 2 · 40%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 60%Moderate 0 · 0%High 0 · 0%

PGE2 vs placebo or no treatment

Serious neonatal morbidity or perinatal death · patients with induction of labour at term

PGE2 showed no clear difference in serious neonatal morbidity or perinatal death compared with placebo or no treatment (low certainty).

1 finding from 1 review

Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term 2014 · Cochrane Headline outcomes only
RR 0.46 [0.09, 2.31]
9 studies · 3638 participants
Low

(7.1) PGE2 (controlled release) vs all PGE2 delivery systems (all women)

Serious neonatal morbidity or perinatal death · patients with induction of labour at term

(7.1) PGE2 (controlled release) showed no clear difference in serious neonatal morbidity or perinatal death compared with all PGE2 delivery systems (all women) (low certainty).

1 finding from 1 review

Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term 2014 · Cochrane Headline outcomes only
RR 0.31 [0.01, 7.62]
2 studies · 320 participants
Low

Vaginal PGE2 pessary vs vaginal PGE2

Serious neonatal morbidity or perinatal death · women with a previous caesarean section, a live singleton fetus (37‐42 weeks of gestation) in cephalic presentation and a reactive…

The review found no eligible studies for this question.

1 finding from 1 review

Methods of term labour induction for women with a previous caesarean section 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious neonatal morbidity or perinatal death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious neonatal morbidity/perinatal death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Methods of term labour induction for women with a previous caesarean section 2017 · Cochrane Headline outcomes only
RR 3 [0.13, 69.7]
1 study · 42 participants
Low

Double‐balloon catheter vs vaginal PGE2

Serious neonatal morbidity or perinatal death · women with a previous caesarean section (subgroup of all women in the study) with intact fetal membranes, cephalic position and…

The review found no eligible studies for this question.

1 finding from 1 review

Methods of term labour induction for women with a previous caesarean section 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found