Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

31 questions · 31 findings · 10 reviews

No studies found 20 · 64.5%GRADE not reported 0 · 0%Very low 7 · 22.6%Low 3 · 9.7%Moderate 1 · 3.2%High 0 · 0%

Summary of findings table ‐ Rifaximin vs placebo or no intervention

Serious adverse events ‐ total number of participants · prevention and treatment of hepatic encephalopathy in people with cirrhosis

Summary of findings table ‐ Rifaximin showed no clear difference in serious adverse events ‐ total number of participants compared with placebo/no intervention (moderate certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events (number) · people with acute pancreatitis
1 finding from 1 review

Summary of findings table ‐ Rifaximin vs placebo or no intervention

Non‐serious adverse events ‐ total number of particiapnts · prevention and treatment of hepatic encephalopathy in people with cirrhosis

It is very uncertain whether summary of findings table ‐ Rifaximin changes non‐serious adverse events ‐ total number of particiapnts compared with placebo/no intervention (very low certainty).

1 finding from 1 review

Palliative care vs usual care

Adverse effects: at least one serious adverse event · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

Palliative care showed no clear difference in serious adverse events Assessed by: number of participants… compared with usual care (low certainty).

1 finding from 1 review