Cochrane · systematic review · CD011384
Pharmacological interventions for acute pancreatitis
Moggia, E, Koti, R, Belgaumkar, AP, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
6
No studies
2
Included studies
NR
No studies 2 · 25%Ungraded 0 · 0%Very low 6 · 75%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings (mortality)
Population: people with acute pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Short‐term mortality | OR 0.81 [0.57, 1.15] | 17 studies · 1058 participants | Very low Downgraded: risk of bias, imprecision |
Long‐term mortality | no estimate extracted | NR | No studies |
Summary of findings (other primary outcomes)
Population: people with acute pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Serious adverse events (proportion) | OR 0.65 [0.37, 1.15] | 5 studies · 304 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events (number) | 0.86 [0.68, 1.07] | 12 studies · 716 participants | Very low Downgraded: risk of bias, imprecision |
Organ failure | OR 0.78 [0.44, 1.38] | 5 studies · 258 participants | Very low Downgraded: risk of bias, imprecision |
Infected pancreatic necrosis | OR 0.82 [0.53, 1.25] | 11 studies · 714 participants | Very low Downgraded: risk of bias, imprecision |
Sepsis | OR 0.42 [0.11, 1.6] | 1 study · 60 participants | Very low Downgraded: risk of bias, imprecision |
Health‐related quality of life | no estimate extracted | NR | No studies |