What do systematic reviews say?

Fluoroquinolones vs amoxicillin

• Head‐to‐head trials of antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 83 participants
  Low

Quinolone vs macrolides

The review found no eligible studies for this question.

• Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Quinolone vs tetracycline

The review found no eligible studies for this question.

• Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fluoroquinolone plus standard regimen vs standard regimen

It is very uncertain whether fluoroquinolone plus standard regimen changes serious adverse events compared with standard regimen alone (very low certainty).

• Fluoroquinolones for treating tuberculosis (presumed drug‐sensitive) 2013 · Cochrane Headline outcomes only
  RR 0.85 [0.4, 1.78]
  1 study · 174 participants
  Very low

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in serious adverse events compared with standard regimen (low certainty).

• Fluoroquinolones for treating tuberculosis (presumed drug‐sensitive) 2013 · Cochrane Headline outcomes only
  RR 1.1 [0.43, 2.8]
  1 study · 433 participants
  Low

Fluoroquinolone substitution for ethambutol in a standard six month regimen vs standard regimen

It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes serious adverse events compared with standard regimen (very low certainty).

• Fluoroquinolones for treating tuberculosis (presumed drug‐sensitive) 2013 · Cochrane Headline outcomes only
  RR 0.93 [0.53, 1.62]
  3 studies · 723 participants
  Very low

Fluoroquinolones vs macrolides

The review found no eligible studies for this question.

• Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Fluoroquinolones vs beta‐lactams

It is very uncertain whether fluoroquinolones changes serious adverse events clinical criteria compared with beta‐lactams (very low certainty).

• Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
  RR 10.9 [0.61, 194.82]
  1 study · 221 participants
  Very low

Ceftriaxone vs fluoroquinolones

The review found no eligible studies for this question.

• Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Cefixime vs fluoroquinolones

The review found no eligible studies for this question.

• Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Cotrimoxazole vs fluoroquinolones

The review found no eligible studies for this question.

• Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found