Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 16 findings · 9 reviews · Airways

No studies found 8 · 50%GRADE not reported 1 · 6.3%Very low 3 · 18.8%Low 1 · 6.3%Moderate 1 · 6.3%High 2 · 12.5%

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

Serious adverse events

The review found no eligible studies for this question.

2 findings from 1 review

Antibiotics vs placebo

Serious adverse events WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…

Antibiotics showed no clear difference in serious adverse events WMD of compared with placebo (moderate certainty).

1 finding from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

Serious adverse events

The review found no eligible studies for this question.

2 findings from 1 review

Vitamin D vs placebo

Proportion of participants with one or more serious adverse events due to any cause · children and adults with predominantly mild to moderate asthma

Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more serious adverse events… compared with placebo (high certainty).

1 finding from 1 review