Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Oxycodone MR vs placebo

Serious adverse events · adults with neuropathic pain (2 studies in peripheral diabetic neuropathy and 1 study in postherpetic neuralgia)

1 finding from 1 review

Oxycodone for neuropathic pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 352 participants
Very low

Oxycodone vs placebo

Serious adverse events · adults with fibromyalgia

1 finding from 1 review

Oxycodone for pain in fibromyalgia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Naloxone + oxycodone prolonged release tablets vs oxycodone

Serious adverse eventsg · people with cancer irrespective of whether they were receiving palliative care opioid‐induced bowel dysfunction

It is very uncertain whether naloxone + oxycodone prolonged release tablets changes serious adverse eventsg compared with oxycodone prolonged‐released tablets (very low certainty).

1 finding from 1 review

Mu‐opioid antagonists for opioid‐induced bowel dysfunction in people with cancer and people receiving palliative care 2022 · Cochrane Headline outcomes only
RR 0.68 [0.44, 1.06]
3 studies · 362 participants
Very low