Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews · Tobacco Addiction

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No studies found 0 · 0%GRADE not reported 1 · 14.3%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Oral and sublingual immunotherapy vs no therapy

Numbers of children with serious adverse events · children with egg allergy

1 finding from 1 review

Oral and sublingual immunotherapy for egg allergy 2018 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 439 participants
Low

Fast‐acting nicotine replacement therapy vs nicotine patch

Overall serious adverse events · people who smoke

1 finding from 1 review

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1252 participants
Very low

Preloading nicotine replacement therapy (NRT) vs standard‐use NRT

Overall serious adverse events · people who smoke

Preloading nicotine replacement therapy (NRT) showed no clear difference in overall serious adverse events compared with standard‐use NRT (low certainty).

1 finding from 1 review

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.11 [0.59, 2.09]
4 studies · 3908 participants
Low

Bupropion plus nicotine replacement therapy (NRT) vs NRT

Serious adverse events · people who smoke

Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in serious adverse events compared with NRT alone (low certainty).

1 finding from 1 review

Antidepressants for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.52 [0.26, 8.89]
4 studies · 657 participants
Low

Longer vs shorter duration of nicotine patch therapy

Overall serious adverse events · people who smoke

1 finding from 1 review

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1173 participants
Very low

Combination vs nicotine replacement therapy monotherapy

Overall serious adverse events · people who smoke

Combination showed no clear difference in overall serious adverse events compared with single‐form nicotine replacement therapy (low certainty).

1 finding from 1 review

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
RR 4.44 [0.76, 25.85]
5 studies · 2888 participants
Low

Intervention not reported

Overall serious adverse events · people who smoke

1 finding from 1 review

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported