What do systematic reviews say?

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

It is very uncertain whether local anaesthetic wound infiltration changes serious adverse events compared with no local anaesthetic wound infiltration (very low certainty).

• Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
  RR 2 [0.19, 21.59]
  7 studies · 539 participants
  Very low

Local anaesthetic wound infiltration before incision vs end of surgery

• Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 43 participants
  Very low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

It is very uncertain whether summary of findings table ‐ Intraperitoneal local anaesthetic changes serious adverse events compared with control (very low certainty).

• Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
  RR 1.07 [0.49, 2.34]
  13 studies · 988 participants
  Very low

Intervention not reported

• Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 137 participants
  Very low