Findings

What do systematic reviews say?

8 questions · 8 findings · 2 reviews · Gut

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No studies found 1 · 12.5%GRADE not reported 4 · 50%Very low 1 · 12.5%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Antibiotics vs placebo

Serious adverse events · Patients with active Crohn's disease

Antibiotic showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
RR 1.7 [0.29, 10.01]
3 studies · 520 participants
Low

Antibiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Serious adverse events · people with active UC

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
GRADE not reported

Antibiotics vs probiotic

Serious adverse events · people with active UC

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
GRADE not reported

Antibiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Serious adverse events · Patients with quiescent ulcerative colitis

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
GRADE not reported

Antibiotics vs no treatment

Serious adverse events · of active and inactive people with ulcerative colitis

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
GRADE not reported

Antibiotics vs placebo

Serious adverse events · people with active UC

Antibiotics showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 1.19 [0.38, 3.71]
8 studies · 691 participants
Low

Antibiotic with anti‐TNF vs placebo with anti‐TNF

Serious adverse events · Patients with active Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics plus probiotics vs placebo or no intervention

Serious adverse events · people with active UC

It is very uncertain whether antibiotics plus probiotics changes serious adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes only
RR 1 [0.07, 15.08]
2 studies · 98 participants
Very low