Etrolizumab vs placebo
Etrolizumab showed no clear difference in serious adverse events compared with placebo (low certainty).
- RR 0.92 [0.36, 2.34]2 studies · 165 participantsLow
Etrolizumab showed no clear difference in serious adverse events compared with placebo (low certainty).
Vedolizumab showed no clear difference in serious adverse events compared with placebo (moderate certainty).
It is very uncertain whether probiotics changes serious adverse events (52 weeks) compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (very low certainty).
Tofacitinib showed no clear difference in serious adverse events (5 mg/10 mg) compared with placebo (low certainty).
Antibiotics showed no clear difference in serious adverse events compared with placebo (low certainty).
It is very uncertain whether antibiotics plus probiotics changes serious adverse events compared with placebo or no intervention (very low certainty).
Once‐daily dosing showed no clear difference in serious adverse events compared with conventional dosing (moderate certainty).
Oral 5‐aminosalicylic acid showed no clear difference in serious adverse events compared with comparator 5‐aminosalicylic acid formulation (low certainty).
Oral 5‐aminosalicylic acid showed no clear difference in serious adverse events compared with placebo (low certainty).