What do systematic reviews say?

Barbiturate treatment vs placebo or no treatment

Barbiturate treatment may leads to lower seizures (clinical or electrographic) compared with placebo or no treatment (low certainty).

• Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia 2016 · Cochrane Headline outcomes only
  RR 0.62 [0.48, 0.81]
  6 studies · 319 participants
  Low