Antiretroviral therapy (any, including cART) vs No antiretroviral medication (treatment-naive)
Salivary immunoglobulin A (SIgA) concentration · Children and adolescents (<18 years) living with HIV (CLWH)
Evidence on salivary IgA in CLWH on versus off ART was divergent and inconclusive (very low certainty).
1 finding from 1 review
- Impact of Antiretroviral Therapy on Oral Health among Children Living with HIV: A Systematic Review and Meta-Analysis. 2022 All outcomesHospitals and AIDS outpatient centres in India, Brazil, and several Asian countriesTwo studies gave divergent results: Subramaniam (2015) reported higher SIgA in children on ART for more than 3 years than pre-ART (8.6 (SD 2.9) vs 6.2 (SD 1.7) mg/dL; p < 0.001), whereas Pomarico (2009) found lower…2 studiesVery low