Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

26 questions · 29 findings · 2 reviews · Tobacco Addiction

No studies found 6 · 20.7%GRADE not reported 5 · 17.2%Very low 4 · 13.8%Low 13 · 44.8%Moderate 1 · 3.4%High 0 · 0%

Longer vs shorter duration of combination nicotine replacement therapy

SAEs · people who smoke

It is very uncertain whether longer changes overall SAEs ‐ 26 weeks versus 8 weeks compared with shorter duration of combination nicotine replacement therapy (very low certainty).

3 findings from 1 review

Higher‐dose vs lower‐dose nicotine patch

SAEs · people who smoke

Higher‐dose showed no clear difference in overall SAEs ‐ 42/44 mg versus 21/22 mg (24 hr patches) compared with lower‐dose nicotine patch (low certainty).

2 findings from 1 review