Findings

What do systematic reviews say?

4 questions · 5 findings · 1 reviews · Schizophrenia

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No studies found 0 · 0%GRADE not reported 1 · 20%Very low 1 · 20%Low 2 · 40%Moderate 1 · 20%High 0 · 0%

ANY INTERMITTENT DRUG TECHNIQUE vs MAINTENANCE THERAPY

Relapse · patients with schizophrenia

ANY INTERMITTENT DRUG TECHNIQUE probably leads to higher relapse: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (moderate certainty).

2 findings from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 2.46 [1.7, 3.54]
7 studies · 436 participants
Moderate
Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 1.7 [0.54, 5.38]
2 studies · 61 participants
Very low

INTERMITTENT (CRISIS INTERVENTION) vs MAINTENANCE THERAPY

Relapse · patients with schizophrenia

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

INTERMITTENT (GRADUALLY INCREASED DRUG‐FREE PERIODS) vs MAINTENANCE THERAPY

Relapse · patients with schizophrenia

INTERMITTENT (GRADUALLY INCREASED DRUG‐FREE PERIODS) may leads to higher relapse: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (low certainty).

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 2.76 [1.63, 4.67]
3 studies · 219 participants
Low

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Relapse · patients with schizophrenia

INTERMITTENT (EARLY‐BASED) may leads to higher relapse: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (low certainty).

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 2.33 [1.32, 4.12]
2 studies · 155 participants
Low