What do systematic reviews say?

Summary of findings ‐ dual therapy: lumacaftor plus ivacaftor vs placebo

The review found no eligible studies for this question.

• Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ dual therapy: tezacaftor plus ivacaftor vs placebo or ivacaftor alone

The review found no eligible studies for this question.

• Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ dual therapy: lumacaftor plus ivacaftor (twice daily) vs placebo

The review found no eligible studies for this question.

• Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Individual TF‐CBT vs Brief PTSD psychoeducation

• Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 49 participants
  Low

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

• Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 39 participants
  Low

Summary of findings ‐ dual therapy: lumacaftor plus ivacaftor (once daily) vs placebo

• Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1061 participants
  Moderate

Summary of findings ‐ triple therapy: elexacaftor‐tezacaftor‐ivacaftor vs control (ivacaftor alone or tezacaftor plus ivacaftor)

The review found no eligible studies for this question.

• Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Yoga vs no breathing exercises

• Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 45 participants
  Moderate

Benralizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1433 participants
  High

Diaphragmatic breathing vs no breathing exercises

• Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Moderate

Mepolizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1285 participants
  Moderate

Benralizumab 10 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 680 participants
  Moderate

Benralizumab 30 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1333 participants
  Moderate

Benralizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1351 participants
  High

Mepolizumab 300 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 451 participants
  Moderate

Mepolizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 911 participants
  Moderate

MX exercise training vs control

• Mixed exercise training for adults with fibromyalgia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 610 participants
  Moderate

Intervention not reported

• Exercise for improving outcomes after osteoporotic vertebral fracture 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 109 participants
  Very low

Intervention not reported

• Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Intervention not reported

• Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 292 participants
  Very low