What do systematic reviews say?

Oral antibiotics vs IV antibiotics

The review found no eligible studies for this question.

• Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Single vs combination IV antibiotics

The review found no eligible studies for this question.

• Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Nebulised antibiotics vs IV antibiotics

The review found no eligible studies for this question.

• Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing)

The review found no eligible studies for this question.

• Combination antimicrobial susceptibility testing for acute exacerbations in chronic infection of Pseudomonas… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics

Summary of findings: Inhaled antibiotics plus IV antibiotics showed no clear difference in quality of life: number of participants achieving MCID compared with IV antibiotics only (low certainty).

• Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
  RR 1.2 [0.61, 2.34]
  1 study · 16 participants
  Low

Summary of findings: Inhaled antibiotics vs IV antibiotics

• Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low