Findings

What do systematic reviews say?

26 questions · 27 findings · 13 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 10 · 37%GRADE not reported 1 · 3.7%Very low 5 · 18.5%Low 8 · 29.6%Moderate 2 · 7.4%High 1 · 3.7%

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Health‐related quality of life Validated self‐reported measures · patients with oesophageal cancer

1 finding from 1 review

Non‐surgical versus surgical treatment for oesophageal cancer 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 165 participants
Very low

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Health‐related quality of life (medium‐term) Self‐assessed questionnaires · patients with oesophageal cancer

1 finding from 1 review

Non‐surgical versus surgical treatment for oesophageal cancer 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical treatment

Quality of life (SRS‐22 Total score) · adolescents with idiopathic scoliosis

1 finding from 1 review

Therapeutic exercises for idiopathic scoliosis in adolescents 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Varicocele treatment vs non‐surgical, delayed, or no treatment

Quality of life · Varicoceles in subfertile men

The review found no eligible studies for this question.

1 finding from 1 review

Surgical or radiological treatment for varicoceles in subfertile men 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs non‐surgical treatment

Quality of life · Adults with symptomatic mild to moderate knee osteoarthritis defined as knee pain and radiographic evidence of non‐end stage…

The review found no eligible studies for this question.

1 finding from 1 review

Surgical interventions for symptomatic mild to moderate knee osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional nicardipine vs Normal saline

Quality of life · men with chronic Peyronie's disease (plaques without calcification)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional betamethasone vs Normal saline

Quality of life · men with Peyronie's disease (not defined)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional collagenase vs placebo

Quality of life · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)

2 findings from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 134 participants
Low
Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 612 participants
Moderate

Potassium paraaminobenzoate vs placebo

Quality of life · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional verapamil vs saline (short‐term)

Quality of life · men with Peyronie's disease (palpable plaque or pain)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional Botox vs placebo

Quality of life · men with Peyronie's disease (stable phase)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Extracorporeal shockwave therapy vs sham

Quality of life · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 130 participants
Low

Penile traction therapy vs no treatment (short‐term)

Quality of life · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 82 participants
Very low

Injectional interferon alpha‐2B vs Normal saline

Quality of life · men with chronic (≥ 12 months) Peyronie's disease (single plaque)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · Adolescent Idiopathic Scoliosis

1 finding from 1 review

Surgical versus non‐surgical interventions in people with adolescent idiopathic scoliosis 2015 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Surgical vs non‐surgical treatment

Quality of Life: SF‐36 (physical component) · people aged over 14 years with displaced intra‐articular calcaneal fractures

1 finding from 1 review

Surgical versus non‐surgical interventions for displaced intra‐articular calcaneal fractures 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 192 participants
Low

Ventilation tubes vs non‐surgical treatment

Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)

The review found no eligible studies for this question.

1 finding from 1 review

Ventilation tubes (grommets) for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surgical vs non‐surgical treatment

Quality of life: EQ‐5D (0: dead to 1: best quality of life) · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)

Surgical showed no clear difference in quality of life: EQ‐5D (0: dead to 1: best quality of life) compared with non‐surgical treatment (high certainty).

1 finding from 1 review

Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes only
MD 0.01
6 studies · 502 participants
High

Early vs delayed mobilisation

Quality of life: EQ‐5D (0: dead to 1: best quality of life) · adults with minimally displaced or displaced (2‐part or 3‐part) proximal humeral fractures treated non‐surgically (5 trials)

1 finding from 1 review

Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Very low

Surgery vs preoperative pharmacological therapy and surgery

Health‐related quality of life · adults with growth‐hormone secreting pituitary adenomas

The review found no eligible studies for this question.

1 finding from 1 review

Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting pituitary… 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found