Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

22 questions · 22 findings · 10 reviews

No studies found 7 · 31.8%GRADE not reported 4 · 18.2%Very low 6 · 27.3%Low 3 · 13.6%Moderate 2 · 9.1%High 0 · 0%

Antidepressants (trazodone 200 mg/day) vs placebo

QoL · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
  • Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes
    short-term (up to 3 months)
    SoF1. Change in QoL short-term (mean Beck Depression Inventory, 0-63, lower better): this single study narratively reported that both intervention and placebo participants were less depressed at trial completion, but…
    1 study · 37 participants
    Very low