What do systematic reviews say?

Summary of findings table ‐ Platinum‐sensitive recurrent EOC: PARPi monotherapy vs chemotherapy alone

• Poly(ADP‐ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 229 participants
  Low

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

The review found no eligible studies for this question.

• Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases 2024 · Cochrane All outcomes
  No studies reported data for this outcome.
  Studies not reported
  No studies found

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

The review found no eligible studies for this question.

• Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri‐implant diseases 2024 · Cochrane All outcomes
  No studies reported data for this outcome.
  Studies not reported
  No studies found

rTMS + pharmacotherapy vs sham rTMS + pharmacotherapy

The review found no eligible studies for this question.

• Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table (subcomparison 1): chemotherapy or targeted therapy plus best supportive care (BSC) vs BSC

• Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1129 participants
  Very low

Summary of findings: Molecular‐targeted therapy plus chemotherapy vs chemotherapy alone

• Molecular‐targeted first‐line therapy for advanced gastric cancer 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 53 participants
  Very low

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

• Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1772 participants
  Very low

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

• Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 156 participants
  Very low

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

• Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy 2015 · Cochrane All outcomes

  High-dose melphalan-based treatment prior to HSCT (haematological cancers)
  Summary of findings 2 (melphalan/HSCT): Quality of life - '1 study assessed this outcome but the data are currently unavailable as the study report and analysis have not yet been completed' (Toro 2013; measured with…
  1 study
  GRADE not reported
• Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy 2015 · Cochrane All outcomes

  Fluorouracil (5FU) treatment for solid cancers
  Summary of findings for the main comparison (5FU solid cancers): Quality of life - 'No studies assessed this outcome'.
  0 studies
  No studies found

Deep transverse massage + physical therapy vs physical therapy alone

The review found no eligible studies for this question.

• Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Positional therapy vs inactive control

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 86 participants
  Moderate

Positional therapy vs continuous positive airway pressure (CPAP)

• Positional therapy for obstructive sleep apnoea 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Penile traction therapy vs no treatment (short‐term)

• Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 82 participants
  Very low

Electrical stimulation plus behavioural therapy vs behavioural therapy alone

• Electrical stimulation with non‐implanted electrodes for overactive bladder in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 82 participants
  Very low

Oestrogen therapy alone vs pelvic floor muscle training (PFMT)

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oestrogen therapy alone vs devices such

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oestrogen therapy alone vs surgery

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oestrogen therapy alone vs no treatment or placebo

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pelvic floor muscle training (PFMT) with urotherapy vs urotherapy alone

The review found no eligible studies for this question.

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Voiding education with uroflow feedback and urotherapy vs urotherapy alone

The review found no eligible studies for this question.

• Conservative interventions for treating functional daytime urinary incontinence in children 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found