What do systematic reviews say?

Metformin 500 mg to 2550 mg per day vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg b.i.d. vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Porter 2020: armodafinil vs placebo

• Interventions for the management of fatigue in adults with a primary brain tumour 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 232 participants
  Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 110 participants
  Low

Leg Club vs nurse home visits

• Interventions for helping people adhere to compression treatments for venous leg ulceration 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 52 participants
  Low

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

• Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Lanadelumab vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 68 participants
  Low

Intervention not reported

The intervention showed no clear difference in quality of life at 6 months Assessed by European Quality of Life‐15 (low certainty).

• Environmental and behavioural interventions for reducing physical activity limitation and preventing falls in older… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 59 participants
  Low

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

The review found no eligible studies for this question.

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  No data were available for this patient-reported outcome in the single included trial.
  0 studies
  No studies found

C1 esterase inhibitor vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Low

Nanofiltered C1 esterase inhibitor vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Intervention not reported

• Education interventions for adults who attend the emergency room for acute asthma 2007 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 356 participants
  Low

Intervention not reported

The intervention showed no clear difference in quality of life at 6 months Assessed by 12‐Item Short Form Health… (low certainty).

• Environmental and behavioural interventions for reducing physical activity limitation and preventing falls in older… 2020 · Cochrane Headline outcomes only
  MD 3.14
  1 study · 28 participants
  Low

Intervention not reported

The intervention showed no clear difference in health‐related quality of life scores, measured by SF‐36 (range 0 to… (low certainty).

• Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps 2014 · Cochrane Headline outcomes only
  MD 0.6
  1 study · 95 participants
  Low

Summary of findings: Picture Exchange Communication System (PECS) vs treatment

The review found no eligible studies for this question.

• Communication interventions for autism spectrum disorder in minimally verbal children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Berotralstat vs placebo or active control

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 130 participants
  Moderate

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

The review found no eligible studies for this question.

• Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found