Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

701 questions · 713 findings · 246 reviews

No studies found 398 · 55.8%GRADE not reported 59 · 8.3%Very low 114 · 16%Low 98 · 13.7%Moderate 40 · 5.6%High 4 · 0.6%

Surgery vs Pharmacological therapy

Health‐related quality of life Mean AcroQoL score (0‐100) · adults with growth‐hormone secreting pituitary adenomas

Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).

1 finding from 1 review

Ball (stud) attachment system vs Bar attachment system

Patient satisfaction / quality of life (validated measure) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review

Ball (stud) attachment system vs Telescopic attachment system

Patient satisfaction / quality of life (validated measure) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review

Ball (stud) attachment system vs Magnetic attachment system

Patient satisfaction / quality of life (validated measure) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review

Surgical vs non‐surgical treatment

Quality of life: EQ‐5D (0: dead to 1: best quality of life) · (mainly older) adults with most types of displaced proximal humeral fracturesa (10 trials)

Surgical showed no clear difference in quality of life: EQ‐5D (0: dead to 1: best quality of life) compared with non‐surgical treatment (high certainty).

1 finding from 1 review