Findings

What do systematic reviews say?

109 questions · 117 findings · 57 reviews

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No studies found 14 · 12%GRADE not reported 18 · 15.4%Very low 17 · 14.5%Low 35 · 29.9%Moderate 20 · 17.1%High 13 · 11.1%

Reablement vs usual home‐care

QoL · adults aged ≥ 65 years

1 finding from 1 review

Time‐limited home‐care reablement services for maintaining and improving the functional independence of older adults 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 249 participants
Very low

Benralizumab 10 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 680 participants
Moderate

Benralizumab 30 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1333 participants
Moderate

Benralizumab 100 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1351 participants
High

Mepolizumab 300 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 451 participants
Moderate

Mepolizumab 100 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 911 participants
Moderate

Mucolytic vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · chronic bronchitis or COPD

1 finding from 1 review

Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2721 participants
Moderate

Combination of manual therapy, exercise, electrotherapy and placebo injection vs glucocorticoid injection

Quality of Life: SF‐36 (physical component) · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Low

Combination of manual therapy, exercise, electrotherapy and placebo injection vs placebo injection

Quality of Life: SF‐36 (physical component) · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Low

Combination of manual therapy, exercise, electrotherapy and glucocorticoid injection vs glucocorticoid injection

Quality of Life: SF‐36 (physical component) · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Low

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Quality of Life: SF‐36 (physical component) · patients with adhesive capsulitis (frozen shoulder)

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 148 participants
High

Cognitive‐behavioural intervention vs controls

Health‐related quality of life end of treatment (0‐80 scale) Higher scores indicate lower health‐related quality of life · patients with fibromyalgia

1 finding from 1 review

Cognitive behavioural therapies for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1238 participants
Low

Intervention not reported

Disease‐specific quality of life QUALEFFO‐41 total score Scale from 0 to 100 Lower scores indicate better quality of life · individuals with osteoporotic vertebral fracture

1 finding from 1 review

Exercise for improving outcomes after osteoporotic vertebral fracture 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 109 participants
Very low

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life) · patients with fibromyalgia

Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty).

1 finding from 1 review

Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia 2018 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 6861 participants
Low

Information or education intervention vs no education

Health‐related quality of life (HRQoL) · adult ICU patients and their carers

1 finding from 1 review

Information or education interventions for adult intensive care unit (ICU) patients and their carers 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 143 participants
Very low

Weight loss vs control

Incontinence‐specific quality of life · adults with urinary incontinence

1 finding from 1 review

Lifestyle interventions for the treatment of urinary incontinence in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

ICU follow‐up services vs standard care or no follow‐up service

Health‐related quality of life (HRQoL) · adult survivors of the ICU, excluding those already in an existing follow‐up or rehabilitation programme

1 finding from 1 review

Follow‐up services for improving long‐term outcomes in intensive care unit (ICU) survivors 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 286 participants
Low

Summary of findings (water exercise vs no exercise

Quality of life St George's Respiratory Questionnaire (SGRQ) score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Water‐based exercise training for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
no estimate extracted
19 participants
Low

Pursed lip breathing vs no breathing exercises

Health‐related quality of life Dyspnoea domain of Hiratsuka scale Scores range from 0 to 100, with lower scores indicating less shortness of breath · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Low

Summary of findings (water exercise vs land exercise)

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Water‐based exercise training for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
no estimate extracted
60 participants
Low