Findings

What do systematic reviews say?

701 questions · 713 findings · 246 reviews

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No studies found 398 · 55.8%GRADE not reported 59 · 8.3%Very low 114 · 16%Low 98 · 13.7%Moderate 40 · 5.6%High 4 · 0.6%

Physical exercise training vs usual care

General health‐related quality of life · children and young adults during and after treatment for childhood cancer

1 finding from 1 review

Physical exercise training interventions for children and young adults during and after treatment for childhood cancer 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Low

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life (SGRQ) ‐ Total scores SGRQ units. Scale from: 0 to 100. · Adults who attend the emergency room for acute asthma

1 finding from 1 review

Education interventions for adults who attend the emergency room for acute asthma 2007 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 356 participants
Low

Psychological therapy vs enhanced or structured care

Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability · people with somatoform disorders and medically unexplained physical symptoms

1 finding from 1 review

Non‐pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 497 participants
Moderate

Psychological therapy vs Waitlist/Usual Care

Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability · people with somatoform disorders and medically unexplained physical symptoms

1 finding from 1 review

Non‐pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 730 participants
Low

Natural products vs placebo

Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability · somatoform disorders in adults

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants with at least 50% improvement in their quality of life ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Neurodynamic mobilisation vs no treatment

Long‐term improvement in functional ability or health‐related quality of life (more than three months) · People with carpal tunnel syndrome on a waiting list for carpal tunnel release

1 finding from 1 review

Exercise and mobilisation interventions for carpal tunnel syndrome 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Tricyclic antidepressants vs placebo

Functional disability and quality of life (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surgical vs conservative interventions

Health‐related quality of life (physical) · adults (aged ≥ 16 years) with acute middle third clavicle fractures

1 finding from 1 review

Surgical versus conservative interventions for treating fractures of the middle third of the clavicle 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 321 participants
Low

Neurodynamic mobilisation vs no treatment

Short‐term improvement in functional ability or health‐related quality of life (hand function) (three months or less) · People with carpal tunnel syndrome on a waiting list for carpal tunnel release

It is very uncertain whether neurodynamic mobilisation changes short‐term improvement in functional ability or health‐related… compared with no treatment (very low certainty).

1 finding from 1 review

Exercise and mobilisation interventions for carpal tunnel syndrome 2012 · Cochrane Headline outcomes only
RR 9 [0.59, 137.65]
1 study · 12 participants
Very low

New‐generation antidepressants vs placebo

Quality of life at post‐treatment Indexed by self‐report measures of quality of life or functional disability · somatoform disorders in adults

1 finding from 1 review

Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 163 participants
Very low

Culturally and literacy adapted self‐management programme vs written information on the same topic

Quality of life – Diabetes‐related quality of life standardised on score 0 (no quality of life) to 100 (perfect quality of life) Time point: short‐term (immediately post‐intervention) · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 288 participants
Very low

Physical activity vs dietary interventions

Quality of life – 12 weeks · people with IBS

1 finding from 1 review

Physical activity for treatment of irritable bowel syndrome 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low

Physical activity vs dietary interventions

Quality of life – 24 weeks · people with IBS

1 finding from 1 review

Physical activity for treatment of irritable bowel syndrome 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low

Intervention not reported

Global quality of life score Multiple measures used. WHO‐Five‐Wellbeing Index (Ledderer 2013) FACT‐G total score (Northouse 2007). Additional study (reported in comments section): SF20 subscales (Blanchard 1996). Higher scores indicate better QoL · informal caregivers of people affected by cancer

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 239 participants
Low

Intervention not reported

Global quality of life score Mulitple measures used. Caregiver Strain Index (Campbell 2007)** FACT‐G total score (Northouse 2007). Additional studies (reported in comments section): SF20 subscales (Blanchard 1996) SF36 social functioning subscale ... · informal caregivers of people affected by cancer

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 265 participants
Low

Bethanechol vs placebo

QoL

The review found no eligible studies for this question.

1 finding from 1 review

Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Suprapubic catheterisation vs intermittent self‐catheterisation

QoL

The review found no eligible studies for this question.

1 finding from 1 review

Postoperative interventions for preventing bladder dysfunction after radical hysterectomy in women with early‐stage… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Multidisciplinary disease management programmes vs usual care

Quality of life (MLHFQ): from 0 to 105 · adults with heart failure

1 finding from 1 review

Disease management interventions for heart failure 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 140 participants
Very low