Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Gut

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Methotrexate vs 6‐mercaptopurine

Clinical remission · patients with induction of remission in ulcerative colitis

It is very uncertain whether methotrexate changes proportion of patients achieved clinical remission compared with 6‐mercaptopurine (very low certainty).

1 finding from 1 review

Methotrexate for induction of remission in ulcerative colitis 2014 · Cochrane Headline outcomes only
RR 0.74 [0.43, 1.29]
1 study · 26 participants
Very low

Methotrexate vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Clinical remission · patients with induction of remission in ulcerative colitis

It is very uncertain whether methotrexate changes proportion of patients achieved clinical remission compared with 5‐aminosalicylic acid (5‐ASA) (very low certainty).

1 finding from 1 review

Methotrexate for induction of remission in ulcerative colitis 2014 · Cochrane Headline outcomes only
RR 2.33 [0.66, 3.64]
1 study · 20 participants
Very low