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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · Neonatal

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Systemic administration of beta‐blockers vs placebo or no treatment

Progression to stage 3 ROP · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers probably leads to lower progression to stage 3 ROP compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Progression to stage 4 or 5 ROP · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers showed no clear difference in progression to stage 4 or 5 ROP compared with placebo or no treatment (moderate certainty).

1 finding from 1 review