Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies including smokers: OR 2.50 (1.74 to 3.59) for preterm birth, significant.
1 finding from 1 review
OR 2.50 [1.74, 3.59]
8 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies excluding participants with co-morbidities: OR 2.53 (1.45 to 4.42) for preterm birth, significant.
1 finding from 1 review
OR 2.53 [1.45, 4.42]
6 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Pregnant women with periodontitis probably have a small increased risk of preterm birth (moderate certainty).
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=2 affected teeth: OR 2.31 (1.60 to 3.34) for preterm birth, significant.
1 finding from 1 review
OR 2.31 [1.60, 3.34]
3 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=4 teeth with PPD >=4 mm and CAL >=3 mm at the same site: OR 2.86 (1.79 to 4.56) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies including participants with history of urinary tract infection: OR 2.38 (1.63 to 3.49) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Study design: cohort: OR 2.07 (1.48 to 2.89) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=1 affected tooth: OR 1.63 (1.16 to 2.31) for preterm birth, significant.
1 finding from 1 review
OR 1.63 [1.16, 2.31]
2 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies excluding smokers: OR 1.71 (0.96 to 3.05) for preterm birth, not significant.
1 finding from 1 review
OR 1.71 [0.96, 3.05]
2 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Continent: North America: OR 2.27 (1.82 to 2.84) for preterm birth, significant.
1 finding from 1 review
OR 2.27 [1.82, 2.84]
3 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Risk of bias: low: OR 2.49 (1.82 to 3.42) for preterm birth, significant.
1 finding from 1 review
OR 2.49 [1.82, 3.42]
9 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Continent: Europe: OR 1.77 (1.28 to 2.44) for preterm birth, significant.
1 finding from 1 review
OR 1.77 [1.28, 2.44]
3 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=3 mm CAL: OR 2.50 (1.60 to 3.90) for preterm birth, significant.
1 finding from 1 review
OR 2.50 [1.60, 3.90]
6 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Periodontitis definition: >=1 mm CAL: OR 2.87 (1.65 to 4.99) for preterm birth, significant.
1 finding from 1 review
OR 2.87 [1.65, 4.99]
2 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Studies including participants with co-morbidities: OR 2.16 (1.54 to 3.03) for preterm birth, significant.
1 finding from 1 review
OR 2.16 [1.54, 3.03]
4 studies
GRADE not reported
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Examined teeth: full mouth without specification on third molars: OR 2.77 (1.72 to 4.44) for preterm birth, significant.
1 finding from 1 review
Periodontitis (exposure) vs No periodontitis
Preterm birth (<37 weeks) · Pregnant women
Risk of bias: high: OR 1.60 (0.75 to 3.44) for preterm birth, not significant.
1 finding from 1 review
OR 1.60 [0.75, 3.44]
2 studies
GRADE not reported
Preterm birth · Women with a multiple pregnancy
Vaginal progesterone showed no clear difference in preterm birth less than 37 weeks compared with no treatment or placebo (moderate certainty).
1 finding from 1 review
Preterm birth less than 28 weeks · Women with a multiple pregnancy
Vaginal progesterone showed no clear difference in preterm birth less than 28 weeks compared with no treatment or placebo (low certainty).
1 finding from 1 review
Preterm birth less than 34 weeks' gestation · Women with a multiple pregnancy
Intramuscular (IM) progesterone may leads to higher preterm birth less than 34 weeks compared with no treatment or placebo (low certainty).
1 finding from 1 review