Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 2 reviews · Oral Health

No studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 0 · 0%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone

Probing pocket depth (PPD/PD) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

Mechanical debridement plus local antimicrobial (minocycline… showed no clear difference in pocket depth (mm) compared with mechanical debridement alone (low certainty).

1 finding from 1 review

Mechanical debridement plus topical minocycline vs Mechanical debridement plus chlorhexidine gel

Change in probing pocket depth (PPD) · Adults with dental implants and peri-implant mucositis at baseline

Mechanical debridement plus topical minocycline showed no clear difference in change in probing pocket depth compared with mechanical debridement plus chlorhexidine gel; GRADE not reported.

1 finding from 1 review

Mechanical debridement plus topical minocycline vs Mechanical debridement plus chlorhexidine gel

Change in probing pocket depth (worst sites) · Adults with dental implants and peri-implant mucositis at baseline

Mechanical debridement plus topical minocycline showed no clear difference in change in probing pocket depth (worst sites) compared with mechanical debridement plus chlorhexidine gel; GRADE not reported.

1 finding from 1 review