Findings

What do systematic reviews say?

4 questions · 4 findings · 3 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 4 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Low socioeconomic position and adverse behavioural factors vs Higher socioeconomic position and fewer adverse behaviours

Systemic inflammation (C-reactive protein) and periodontal disease progression · General-population adults (German cohort)

In one 5-year longitudinal study, accumulation of low socioeconomic and behavioural factors was associated with greater periodontal disease progression and higher C-reactive protein; not pooled (ungraded).

1 finding from 1 review

Social-Biological Interactions in Oral Disease: A 'Cells to Society' View. 2016 All outcomes
5-year follow-up · General adult population, Germany (Study of Health in Pomerania)
no estimate extracted
1 study · 3300 participants
GRADE not reported

Slum / urban-disadvantaged setting vs Non-slum urban / general-urban / national population

Periodontal disease prevalence · Adult residents of slums and non-slum urban settings of LMICs

Periodontal disease prevalence is high (23%-99%) across LMIC urban/slum populations; ungraded.

1 finding from 1 review

Systematic review of oral health in slums and non-slum urban settings of Low and Middle-Income Countries (LMICs):… 2024 All outcomes
Cross-sectional · Urban slums and non-slum/general-urban settings, LMICs
Periodontal disease affected all ages, was more pronounced in older groups, and ranged from 23% to 99%, generally higher than dental caries; bleeding gum/gingivitis contributed the largest component.
9 studies
GRADE not reported

Job-related or family-related stress and pessimistic attitude to life vs Lower stress and no pessimistic attitude

Periodontal disease and serum IL-1β IL-6 and cortisol · Patients with aggressive or chronic periodontitis at a university periodontology department

No correlation was reported between immunological markers cortisol and registered stress values; untreated aggressive periodontitis was accompanied by pessimistic attitude and elevated serum IL-6.

1 finding from 1 review

Social-Biological Interactions in Oral Disease: A 'Cells to Society' View. 2016 All outcomes
Marburg Germany
no estimate extracted
1 study · 80 participants
GRADE not reported

Higher JIA disease activity/severity (e.g., high JADAS/activity scores, polyarticular RF-negative subtype, active disease, anti-TNFalpha or cyclosporine medication) vs Lower JIA disease activity / inactive or milder JIA

Prevalence and severity of oral and TMJ diseases/conditions (periodontal status and dental caries) · Children and adolescents with juvenile idiopathic arthritis (JIA)

Some studies suggested greater JIA disease activity/severity (and certain medications) was associated with worse periodontal and caries outcomes, but small samples meant no solid conclusion could be drawn (ungraded).

1 finding from 1 review

Oral health in children and adolescents with juvenile idiopathic arthritis - a systematic review and meta-analysis. 2019 All outcomes
Multiple countries (Brazil, Sweden, Germany); paediatric rheumatology/dental settings
Higher JIA disease activity/severity was associated with worse oral outcomes in several studies: JADAS and global activity scores correlated positively with DMFT and gingival indices [27]; a polyarticular RF-negative…
Studies not reported
GRADE not reported