Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) vs placebo or control
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Analgesic (any: NSAID, paracetamol, local anaesthetic or opioid) probably leads to lower pain intensity (VAS 0-100 mm) compared with control (placebo or no treatment) (moderate certainty).
3 findings from 1 review
- Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes2 hoursMD -11.66 [-16.15, -7.17]10 studies · 685 participantsModerate
- Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes24 hoursMD -21.19 [-28.31, -14.06]12 studies · 1012 participantsModerate
- Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes6 hoursMD -24.27 [-31.44, -17.11]9 studies · 535 participantsModerate