Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Hope-based intervention showed no clear difference in pain intensity compared with pain education; GRADE not reported.
1 finding from 1 review
Overall symptoms, pain and headache (relief from symptoms assessed by global measures) · Adults aged 18 years or older with clinically diagnosed TMD (exhibiting two or more of the listed signs and/or symptoms)
The review found no eligible studies for this question.
1 finding from 1 review
Jaw pain (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral cyclobenzaprine (muscle relaxant) showed no clear difference in jaw pain (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Jaw pain (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral clonazepam (benzodiazepine) showed no clear difference in jaw pain (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with behavioural therapy (counselling, CBT, relaxation, self-care… (very low certainty).
1 finding from 1 review
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with another occlusal splint with a different mechanism of action (very low certainty).
1 finding from 1 review
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).
1 finding from 1 review
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with pharmacological therapy (very low certainty).
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain at rest compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain at rest compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Change in pain index · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral propranolol (beta-blocker) showed no clear difference in change in pain index compared with placebo; GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral celecoxib (COX-2 inhibitor) showed no clear difference in pain intensity (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral naproxen (NSAID) led to lower pain intensity (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in pain intensity (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Muscle pain when chewing · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review