High dose of manipulation showed no clear difference in chronic neck pain and CGH Intermediate‐term compared with low dose of manipulation (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
Moderate

Manipulation vs exercise

Acute and subacute neck pain Long‐term · patients with acute and subacute neck pain

Manipulation showed no clear difference in acute and subacute neck pain Long‐term compared with exercise (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
SMD 0.06
1 study · 182 participants
Moderate

Manipulation vs mobilisation

Acute and subacute neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in acute and subacute neck pain Short‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 176 participants
Moderate

Manipulation vs mobilisation

Subacute and chronic neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in subacute and chronic neck pain Short‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 269 participants
Moderate

Manipulation vs mobilisation

Acute and subacute neck pain Intermediate‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in acute and subacute neck pain Intermediate‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 177 participants
Moderate

Manipulation vs exercise

Acute and subacute neck pain Intermediate‐term · patients with acute and subacute neck pain

Manipulation showed no clear difference in acute and subacute neck pain Intermediate‐term compared with exercise (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 182 participants
Moderate

Manipulation vs exercise

Acute and subacute neck pain Immediate post‐treatment · patients with acute and subacute neck pain

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 182 participants
Moderate

Manipulation vs mobilisation

Acute, subacute and chronic neck pain Intermediate‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in acute, subacute and chronic neck pain Intermediate‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 446 participants
Moderate

Manipulation (thoracic) vs inactive control

Chronic neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation (thoracic) showed no clear difference in chronic neck pain Short‐term compared with inactive control (low certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 111 participants
Low

Manipulation (thoracic) vs inactive control

Chronic neck pain Intermediate‐term · patients with acute, subacute and chronic neck pain

Manipulation (thoracic) showed no clear difference in chronic neck pain Intermediate‐term compared with inactive control (low certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 111 participants
Low

Manipulation (cervical) vs oral medicine

Acute and subacute neck pain Long‐term · patients with acute and subacute neck pain

Manipulation (cervical) showed no clear difference in acute and subacute neck pain Long‐term compared with oral medicine (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 181 participants
Moderate

Manipulation (thoracic) vs inactive control

Acute and subacute neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation (thoracic) showed no clear difference in acute and subacute neck pain Short‐term compared with inactive control (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 242 participants
Moderate

Manipulation (cervical) vs oral medicine

Acute and subacute neck pain Intermediate‐term · patients with acute and subacute neck pain

Manipulation (cervical) showed no clear difference in acute and subacute neck pain Intermediate‐term compared with oral medicine (moderate certainty).

1 finding from 1 review

Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 182 participants
Moderate

Spinal manipulative therapy vs inert interventions

Pain VAS 0‐100 (higher means worse) · adults with chronic low‐back pain

2 findings from 1 review

Spinal manipulative therapy for chronic low‐back pain 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 72 participants
Very low
Spinal manipulative therapy for chronic low‐back pain 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 70 participants
Very low

Spinal manipulative therapy vs other interventions

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with chronic low‐back pain

3 findings from 1 review

Spinal manipulative therapy for chronic low‐back pain 2011 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1405 participants
High
Spinal manipulative therapy for chronic low‐back pain 2011 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1074 participants
Moderate
Spinal manipulative therapy for chronic low‐back pain 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1285 participants
High