Cochrane · systematic review · CD008112

Spinal manipulative therapy for chronic low‐back pain

Rubinstein, SM, van Middelkoop, M, Assendelft, WJJ, et al. · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library

Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
24
current version
GRADE rated
24
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 11 · 45.8%Low 2 · 8.3%Moderate 3 · 12.5%High 8 · 33.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Spinal manipulative therapy compared to inert interventions for chronic low‐back pain

Population: patients with chronic low‐back pain
4 questions
OutcomeEffectEvidenceStatus / GRADE
Pain VAS. Scale from 0‐100 (worse pain).
Spinal manipulative therapy vs inert interventions
no estimate extracted1 study · 72 participantsVery low
Downgraded: risk of bias
Pain VAS. Scale from 0‐100 (worse pain).
Spinal manipulative therapy vs inert interventions
no estimate extracted1 study · 70 participantsVery low
Downgraded: risk of bias
Recovery at 1 month
Spinal manipulative therapy vs inert interventions
RR 1.03 [0.49, 2.19]1 study · 72 participantsVery low
Downgraded: risk of bias
Recovery at 3 months
Spinal manipulative therapy vs inert interventions
RR 0.96 [0.56, 1.65]1 study · 70 participantsVery low
Downgraded: risk of bias

spinal manipulative therapy (SMT) compared to sham SMT for chronic LBP

Population: patients with chronic LBP
6 questions
OutcomeEffectEvidenceStatus / GRADE
Pain VAS. Scale from: 0‐100 (worse pain).
spinal manipulative therapy (SMT) vs sham SMT
no estimate extracted3 studies · 148 participantsVery low
Downgraded: risk of bias
Pain VAS. Scale from: 0‐100 (worse pain).
spinal manipulative therapy (SMT) vs sham SMT
no estimate extracted1 study · 55 participantsVery low
Downgraded: risk of bias
Pain VAS. Scale from: 0‐100 (worse pain).
spinal manipulative therapy (SMT) vs sham SMT
no estimate extracted1 study · 51 participantsVery low
Downgraded: risk of bias
Functional status Roland Morris Disability Questionnaire. Scale from 0 to 24 (worse function).
spinal manipulative therapy (SMT) vs sham SMT
no estimate extracted1 study · 65 participantsVery low
Downgraded: risk of bias
Functional status Roland Morris Disability Questionnaire. Scale from: 0 to 24 (worse function).
spinal manipulative therapy (SMT) vs sham SMT
no estimate extracted1 study · 55 participantsVery low
Downgraded: risk of bias
Functional status Roland Morris Disability Questionnaire. Scale from: 0 to 24 (worse function).
spinal manipulative therapy (SMT) vs sham SMT
no estimate extracted1 study · 51 participantsVery low
Downgraded: risk of bias

Spinal manipulative therapy compared to all other interventions for chronic low‐back pain

Population: patients with chronic low‐back pain
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain VAS. Scale from: 0‐100 (worse pain).
Spinal manipulative therapy vs all other interventions
no estimate extracted6 studies · 1405 participantsHigh
Pain VAS. Scale from: 0‐100 (worse pain).
Spinal manipulative therapy vs all other interventions
no estimate extracted5 studies · 1074 participantsModerate
Pain VAS. Scale from: 0‐100 (worse pain).
Spinal manipulative therapy vs all other interventions
no estimate extracted3 studies · 1285 participantsHigh
Functional status Roland Morris Disability Questionnaire. Scale from: 0 to 24 (worse function).
Spinal manipulative therapy vs all other interventions
no estimate extracted6 studies · 1402 participantsHigh
Functional status Roland Morris Disability Questionnaire. Scale from: 0 to 24 (worse function).
Spinal manipulative therapy vs all other interventions
no estimate extracted6 studies · 1323 participantsModerate
Functional status Roland Morris Disability Questionnaire. Scale from 0 to 24 (worse function).
Spinal manipulative therapy vs all other interventions
no estimate extracted4 studies · 1418 participantsHigh
Recovery at 1 month
Spinal manipulative therapy vs all other interventions
RR 1.2 [1.04, 1.37]3 studies · 370 participantsModerate
Downgraded: risk of bias

spinal manipulative therapy plus any intervention compared to the intervention alone for chronic LBP

Population: patients with chronic LBP
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain VAS. Scale from: 0‐100 (worse pain).
spinal manipulative therapy plus any intervention vs the intervention alone
no estimate extracted3 studies · 228 participantsLow
Downgraded: risk of bias
Pain VAS. Scale from: 0‐100 (worse pain).
spinal manipulative therapy plus any intervention vs the intervention alone
no estimate extracted2 studies · 1016 participantsHigh
Pain VAS. Scale from: 0‐100 (worse pain).
spinal manipulative therapy plus any intervention vs the intervention alone
no estimate extracted2 studies · 1000 participantsHigh
Functional status Roland Morris Disability Questionnaire. Scale from: 0 to 24 (worse function).
spinal manipulative therapy plus any intervention vs the intervention alone
no estimate extracted2 studies · 156 participantsLow
Downgraded: risk of bias
Functional status Roland Morris Disability Questionnaire. Scale from: 0 to 24 (worse function) .
spinal manipulative therapy plus any intervention vs the intervention alone
no estimate extracted2 studies · 1078 participantsHigh
Functional status Roland Morris Disability Questionnaire. Scale from: 0 to 24 (worse function).
spinal manipulative therapy plus any intervention vs the intervention alone
no estimate extracted1 study · 994 participantsHigh
Recovery at one month
spinal manipulative therapy plus any intervention vs the intervention alone
RR 3.4 [1.12, 10.28]1 study · 32 participantsVery low
Downgraded: risk of bias