Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

17 questions · 17 findings · 7 reviews · Headline outcomes only

No studies found 10 · 58.8%GRADE not reported 0 · 0%Very low 5 · 29.4%Low 1 · 5.9%Moderate 1 · 5.9%High 0 · 0%

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Adverse (mild) effects in the mother · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes adverse (mild) effects in the mother compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects experienced by mother and/or fetus or nursing baby · women with a history of postnatal depression
1 finding from 1 review

Intervention not reported

Adverse effects experienced by mother and/or foetus or nursing baby · women with a history of postnatal depression
1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Other adverse effects · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

The review found no eligible studies for this question.

1 finding from 1 review

Low molecular weight heparin vs no prophylaxis

All adverse effects, including allergies at injection site, minor and major bleeding, others ( · adults undergoing KA

Low‐molecular‐weight heparin showed no clear difference in all adverse effects, including allergies at injection site, minor… compared with no prophylaxis (moderate certainty).

1 finding from 1 review