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Evidence found and GRADE certainty

104 questions · 140 findings · 19 reviews

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No studies found 11 · 7.9%GRADE not reported 103 · 73.6%Very low 14 · 10%Low 2 · 1.4%Moderate 5 · 3.6%High 5 · 3.6%

Higher parental / maternal education vs Lower parental education (reference)

Oral health-related quality of life · Adolescents (10-19 years)

Higher parental education is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents from families with higher incomes and higher levels of maternal education have better OHRQoL scores [34]. Children from families with high income, parental education and family economy had better OHRQoL [42].
    Studies not reported
    GRADE not reported

Malocclusion vs Absence/lower severity of malocclusion

Oral health-related quality of life · Adolescents (10-19 years)

Malocclusion is associated with worse oral health-related quality of life in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review

Favorable family structure (being an only child; nuclear family) vs Having siblings / non-nuclear family structure

Oral health-related quality of life · Adolescents (10-19 years)

Being an only child and growing up in a nuclear family are associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Being an only child, growing up in your nuclear family or family structure, household conditions, and number of people per household and maternal age are predictors of better OHRQoL [43].
    Studies not reported
    GRADE not reported

Treatment of traumatic dental injury vs Untreated dental trauma

Oral health-related quality of life · Adolescents (10-19 years)

Treating traumatic dental injuries reduces their negative impact on OHRQoL in adolescents (narrative synthesis; included review reports low certainty; no pooled estimate or GRADE rating by the umbrella review).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Treatment of TDI reduces the negative impact on OHRQoL in adolescents, based on parental perception [33]. Treatment of traumatic dental injuries reduces the impact on the OHRQoL with low evidence [46].
    Studies not reported
    GRADE not reported

Toothache vs No dental pain

Oral health-related quality of life · Adolescents (10-19 years)

Toothache/dental pain is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Toothache, DMT and tooth loss have a high impact on OHRQoL in adolescentes [26]. There is low evidence that dental pain has a negative impact on OHRQoL [37].
    Studies not reported
    GRADE not reported

Access to dental care / health services vs No / limited access to dental care

Oral health-related quality of life · Adolescents (10-19 years)

Access to dental care is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    having parents who can provide dental care and safe housing are positive predictors for OHRQoL. access to dental care and the performance of health promotion programs are directly proportional to OHRQoL in adolescents.
    Studies not reported
    GRADE not reported

Skin color / ethnicity vs Reference skin color / ethnicity

Oral health-related quality of life · Adolescents (10-19 years)

There is no concrete evidence on the impact of skin color/ethnicity on OHRQoL in adolescents (evidence gap; narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Biological data such as skin color and age have no concrete evidence about this impact in the OHRQoL. Important aspects like gender and skin color did not have their level of impact clarified.
    Studies not reported
    GRADE not reported

Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers)

Oral health-related quality of life · Children and adolescents with juvenile idiopathic arthritis (JIA)

Evidence on OHRQoL was limited: one study found no significant difference between groups while another found orofacial symptoms affected daily life more in JIA; no pooled estimate (ungraded).

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Oral health-related quality of life · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in oral-health-related quality of life (OHIP-14) compared with clinical examination with 6-month recall (high certainty).

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Oral health-related quality of life · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in oral-health-related quality of life (OHIP-14) compared with clinical examination with 24-month recall (high certainty).

1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Oral health-related quality of life · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in oral-health-related quality of life (OHIP-14) compared with clinical examination with 6-month recall (high certainty).

1 finding from 1 review

Younger children's age (3-5 years) vs Older children (>5 years)

Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years

Children aged 3 years had higher odds of poor OHRQoL than older children (OR 2.00, 95% CI 1.42-2.57; 2 studies; ungraded).

2 findings from 1 review

All exposure-OHRQoL estimates pooled for publication-bias correction (meta-trim sensitivity); specific exposure set not defined in source vs Not specified

Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years

A trim-and-fill sensitivity analysis pooling every exposure estimate gave an overall OR of 0.17 (95% CI 0.13-0.21) after correcting for significant publication bias (Fig. 13); this combined estimate spans heterogeneous exposures and is a publication-bias sensitivity result (ungraded).

1 finding from 1 review

Periodontal disease (present) vs Individuals without periodontal disease (by LOA)

Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years

Periodontal disease was associated with higher odds of poor OHRQoL (OR 1.15, 95% CI 1.12-1.18; 3 studies; no heterogeneity; ungraded).

1 finding from 1 review

Higher dental caries experience vs Caries-free controls

Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years

Higher dental caries experience was associated with substantially higher odds of poor OHRQoL (OR 1.66, 95% CI 1.43-1.88; 6 studies; high heterogeneity I2=83.5%; ungraded).

1 finding from 1 review

Low maternal education (<=6 years of schooling) vs Higher maternal education (>6 years)

Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years

Lower maternal education was associated with poor OHRQoL (OR 1.12, 95% CI 1.00-1.23; 4 studies; high heterogeneity; CI lower bound at the null; ungraded).

1 finding from 1 review

Orthodontic treatment need vs No orthodontic treatment need

Poor oral health-related quality of life (OHRQoL) · Children aged 3-12 years

Orthodontic treatment need was associated with modestly higher odds of poor OHRQoL (OR 1.13, 95% CI 1.07-1.18; 3 studies; ungraded).

1 finding from 1 review

Silver diamine fluoride (SDF) vs placebo

Oral health-related quality of life · Children with dental caries

SDF did not significantly differ from placebo for oral health-related quality of life in children (MD 0.03, 95% CI -0.16 to 0.22; ungraded).

1 finding from 1 review