What do systematic reviews say?

5‐HT3 antagonists vs placebo

5‐HT3 antagonists may leads to lower nausea ‐ intraoperative compared with placebo (low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.55 [0.42, 0.71]
  12 studies · 1419 participants
  Low

Anticholinergic medication vs placebo

Anticholinergics may leads to lower nausea ‐ intraoperative compared with placebo (low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.67 [0.51, 0.87]
  4 studies · 453 participants
  Low

Sedation vs placebo

Sedatives probably leads to lower nausea ‐ intraoperative compared with placebo (moderate certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.65 [0.51, 0.82]
  8 studies · 593 participants
  Moderate

Acupuncture or acupressure vs placebo

It is very uncertain whether acupressure/acupuncture changes nausea ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.55 [0.41, 0.74]
  9 studies · 1221 participants
  Very low

Dopamine antagonists vs placebo

It is very uncertain whether dopamine antagonists changes nausea ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.38 [0.27, 0.52]
  15 studies · 1180 participants
  Very low

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes nausea ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.56 [0.37, 0.83]
  6 studies · 609 participants
  Very low

Antihistamines vs placebo

It is very uncertain whether antihistamines changes nausea ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.99 [0.47, 2.11]
  1 study · 149 participants
  Very low

Opioid antagonists vs placebo

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Ginger vs placebo

It is very uncertain whether ginger changes nausea ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.66 [0.36, 1.21]
  2 studies · 331 participants
  Very low