Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

110 questions · 117 findings · 47 reviews · Gynaecology and Fertility

No studies found 32 · 27.4%GRADE not reported 0 · 0%Very low 38 · 32.5%Low 36 · 30.8%Moderate 10 · 8.5%High 1 · 0.9%

Summary of findings table ‐ ICSI vs c‐IVF

Multiple pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in multiple Pregnancy compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Multiple pregnancy rate · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in multiple pregnancy rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Oestrogen vs no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Embryo culture with low oxygen concentration vs embryo culture with atmospheric oxygen concentration

Multiple pregnancy rate · Patients with multiple pregnancy rate

Embryo culture with low oxygen concentration showed no clear difference in multiple‐pregnancy rate compared with embryo culture with atmospheric oxygen concentration (low certainty).

1 finding from 1 review