What do systematic reviews say?

Therapeutic or non‐prophylactic platelet transfusion vs prophylactic platelet transfusion

• A therapeutic‐only versus prophylactic platelet transfusion strategy for preventing bleeding in patients with… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 629 participants
  GRADE not reported

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in mortality from all causes up to 30 days from study entry compared with higher transfusion threshold (20,000 or 30,000) (low certainty).

• Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for… 2015 · Cochrane Headline outcomes only
  RR 1.78 [0.83, 3.81]
  1 study · 255 participants
  Low

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in mortality from all causes up to 30 days from study entry compared with high‐dose schedule (low certainty).

• Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
  RR 1.33 [0.5, 3.54]
  1 study · 849 participants
  Low

Prophylactic platelet transfusions with high‐dose schedule vs standard‐dose strategies

Prophylactic platelet transfusions with high‐dose schedule showed no clear difference in mortality from all causes up to 30 days from study entry compared with standard‐dose schedule (low certainty).

• Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
  RR 1.71 [0.51, 5.81]
  1 study · 855 participants
  Low

Prophylactic platelet transfusions with low‐dose schedule vs prophylactic platelet transfusions with standard‐dose schedule

Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in mortality from all causes up to 30 days from study entry compared with prophylactic platelet transfusions with standard‐dose schedule (low certainty).

• Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
  RR 2.04 [0.7, 5.93]
  3 studies · 1070 participants
  Low