Findings

What do systematic reviews say?

7 questions · 7 findings · 4 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 1 · 14.3%Very low 3 · 42.9%Low 2 · 28.6%Moderate 1 · 14.3%High 0 · 0%

Montelukast vs placebo

All‐cause mortality Deaths · children with acute bronchiolitis

Montelukast showed no clear difference in all‐cause mortality Deaths compared with placebo; GRADE not reported.

1 finding from 1 review

Leukotriene inhibitors for bronchiolitis in infants and young children 2015 · Cochrane Headline outcomes only
RR 2.51 [0.12, 52.16]
1 study · 952 participants
GRADE not reported

Intervention not reported

Mortality All‐cause death · Pregnant women (parity 0‐1)

It is very uncertain whether the intervention changes mortality All‐cause death (very low certainty).

1 finding from 1 review

Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment 2014 · Cochrane Headline outcomes only
RR 1.15 [0.44, 3.06]
3 studies · 2097 participants
Very low

Intervention not reported

Mortality All‐cause death · Pregnant women (parity 2+)

It is very uncertain whether the intervention changes mortality All‐cause death (very low certainty).

1 finding from 1 review

Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment 2014 · Cochrane Headline outcomes only
RR 1.47 [0.42, 5.21]
1 study · 2239 participants
Very low

Intervention not reported

Mortality All‐cause death · Pregnant women (all parities)

The intervention showed no clear difference in mortality All‐cause death (low certainty).

1 finding from 1 review

Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment 2014 · Cochrane Headline outcomes only
RR 0.84 [0.25, 2.74]
4 studies · 6026 participants
Low

Intervention not reported

Mortality All‐cause death · Pregnant women (parity 0‐1)

It is very uncertain whether the intervention changes mortality All‐cause death (very low certainty).

1 finding from 1 review

Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment 2014 · Cochrane Headline outcomes only
RR 1.15 [0.44, 3.06]
2 studies · 2097 participants
Very low

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

All‐cause mortality (number of deaths during trial) · preschool and school‐age children

1 finding from 1 review

Point‐of‐use fortification of foods with micronutrient powders containing iron in children of preschool and school‐age 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 115 participants
Low

Inositol supplementation IV initially followed by enteral administration (repeat doses of 80 mg/kg/day) in preterm infants born at less than 30 weeks' PMA vs placebo

All‐cause mortality (outcome collected through first event: death, hospital discharge, hospital transfer, or 120 days after birth) · preterm infants with or at risk of respiratory distress syndrome

Inositol supplementation IV initially followed by enteral… showed no clear difference in all‐cause mortality (outcome collected through first event: death,… compared with placebo (moderate certainty).

1 finding from 1 review

Inositol in preterm infants at risk for or having respiratory distress syndrome 2019 · Cochrane Headline outcomes only
RR 1.35 [0.91, 2]
2 studies · 701 participants
Moderate