Findings

What do systematic reviews say?

4 questions · 4 findings · 3 reviews · Heart

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 1 · 25%Moderate 1 · 25%High 0 · 0%

Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding

It is very uncertain whether PCC changes mortality (30‐day) compared with FVIIa (very low certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 1.07 [0.38, 3.03]
3 studies · 278 participants
Very low

Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding

PCC showed no clear difference in mortality (30‐day) compared with standard treatment (moderate certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 0.53 [0.12, 2.35]
2 studies · 149 participants
Moderate

30‐day mortality4 · individuals with atrial fibrillation who are undergoing cardiac surgery

The intervention showed no clear difference in 30‐day mortality4 (low certainty).

1 finding from 1 review

Concomitant atrial fibrillation surgery for people undergoing cardiac surgery 2016 · Cochrane Headline outcomes only
RR 1.25 [0.71, 2.2]
18 studies · 1566 participants
Low

Hospital or 30‐day mortality

It is very uncertain whether the intervention changes hospital or 30‐day mortality (very low certainty).

1 finding from 1 review