Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

17 questions · 17 findings · 6 reviews · Vascular

No studies found 1 · 5.9%GRADE not reported 0 · 0%Very low 6 · 35.3%Low 6 · 35.3%Moderate 1 · 5.9%High 3 · 17.6%

Summary of findings: Fibrin sealant vs usual care

All‐cause mortality up to 30 days · people aged 18 and over undergoing vascular surgery

It is very uncertain whether summary of findings: Fibrin sealant changes all‐cause mortality up to 30 days compared with usual care (very low certainty).

1 finding from 1 review

Intervention not reported

Mortality within · Individuals with peripheral arterial disease

The intervention showed no clear difference in mortality within (high certainty).

1 finding from 1 review

Intervention not reported

Procedural mortality · Individuals with peripheral arterial disease

The intervention showed no clear difference in procedural mortality (high certainty).

1 finding from 1 review

Remote ischaemic preconditioning (RIPC) vs no RIPC

Perioperative mortality · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in perioperative mortality (within 1 month after operation) compared with no RIPC (moderate certainty).

1 finding from 1 review