Findings

What do systematic reviews say?

8 questions · 9 findings · 4 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 11.1%Low 4 · 44.4%Moderate 1 · 11.1%High 3 · 33.3%

Disease specific mortality · patients with Early Vulvar Cancer

Primary Groin Radiotherapy showed no clear difference in disease specific mortality compared with primary Groin Surgery (low certainty).

1 finding from 1 review

Primary groin irradiation versus primary groin surgery for early vulvar cancer 2011 · Cochrane Headline outcomes only
RR 3.7 [0.87, 15.8]
1 study · 52 participants
Low

All‐cause mortality · People undergoing radiation therapy for head and neck cancer

Hyperbaric oxygen leads to lower mortality compared with air breathing to enhance the effectiveness of radiotherapy (high certainty).

1 finding from 1 review

Hyperbaric oxygenation for tumour sensitisation to radiotherapy 2018 · Cochrane Headline outcomes only
RR 0.83 [0.7, 0.98]
9 studies · 710 participants
High

All‐cause mortality · People undergoing radiotherapy for uterine cervical cancer

Hyperbaric oxygen showed no clear difference in mortality compared with air breathing (high certainty).

1 finding from 1 review

Hyperbaric oxygenation for tumour sensitisation to radiotherapy 2018 · Cochrane Headline outcomes only
RR 0.88 [0.69, 1.11]
4 studies · 728 participants
High

All‐cause mortality · participants with cancer treated with radiotherapy (with or without chemotherapy)

1 finding from 1 review

All‐cause mortality · participants with cancer treated with radiotherapy (with or without chemotherapy)

2 findings from 1 review

All‐cause mortality · Adults undergoing pelvic radiotherapy

1 finding from 1 review

All‐cause mortality · participants with cancer treated with chemotherapy

1 finding from 1 review

Mortality with urinary bladder cancer · People with any one of a mixed group of cancers

Hyperbaric oxygen showed no clear difference in mortality with urinary bladder cancer compared with air breathing (high certainty).

1 finding from 1 review

Hyperbaric oxygenation for tumour sensitisation to radiotherapy 2018 · Cochrane Headline outcomes only
RR 0.97 [0.74, 1.27]
4 studies · 330 participants
High