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Evidence found and GRADE certainty

8 questions · 8 findings · 6 reviews · Anaesthesia

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No studies found 1 · 12.5%GRADE not reported 2 · 25%Very low 4 · 50%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Mortality within the longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes all‐cause mortality within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Inhaled NO vs placebo or conventional therapy

Mortality before hospital discharge · all infants and children with congenital heart disease having postoperative management of pulmonary hypertension

It is very uncertain whether inhaled nitric oxide changes mortality prior to discharge1 compared with placebo or conventional therapy (very low certainty).

1 finding from 1 review

PEEP vs zero end‐expiratory pressure (ZEEP) during mechanical ventilation

Postoperative mortality · adult participants given general anaesthesia

It is very uncertain whether PEEP changes postoperative mortality compared with zero end‐expiratory pressure (ZEEP) during mechanical ventilation (very low certainty).

1 finding from 1 review

Preoperative inspiratory muscle training vs usual care, non‐exercise intervention

Mortality In the early postoperative period (≤ 30 days) · adult participants undergoing cardiac and major abdominal surgery

It is very uncertain whether preoperative inspiratory muscle training changes all‐cause mortality within 30 days during postoperative period compared with usual care, non‐exercise intervention (very low certainty).

1 finding from 1 review